the total number of vaccine doses administered during the study period was obtained from the centers for disease control and prevention (cdc) covid-19 data tracker. vaers reports were reviewed by cdc physicians and public health professionals to verify that cases met the definitions for probable myocarditis (new concerning symptoms, abnormal cardiac test results, and no other identifiable cause of findings) or confirmed myocarditis (histopathological or cardiac magnetic resonance imaging [cmr] evidence of myocarditis). among individuals meeting the case definition for myocarditis, 1,195 (73%) were <30 years of age, and 1,334 (82%) were male. reporting rates of myocarditis were highest in males aged 12-15 years (70.7 per million doses), 16-17 years (105.9 per million doses), and 18-24 years (52.4 per million doses of bnt162b2 and 56.3 per million doses of mrna-1273), after the second vaccine dose.
among individuals with confirmed myocarditis <30 years of age, 89% presented with chest pain/pressure/discomfort, 29.6% with dyspnea, and 8% with palpitations. of the 96.4% of patients who were hospitalized, none died, and 98% had been discharged from the hospital at the time of writing. based on passive surveillance reporting, myocarditis is a rare adverse event following mrna-based covid-19 vaccination and occurs most commonly in adolescent boys and young men. further study will be needed to evaluate myocarditis risk after booster vaccination.
cdc and its partners are actively monitoring reports of myocarditis and pericarditis after covid-19 vaccination. myocarditis is inflammation of the heart muscle, and pericarditis is inflammation of the outer lining of the heart. learn more about myocarditis and pericarditis.external icon seek medical care if you or your child have symptoms of these conditions after covid-19 vaccination.
seek medical care if you or your child have any of the specific or general symptoms of myocarditis or pericarditis especially if it’s within a week after covid-19 vaccination. cdc continues to recommend that everyone ages 5 years and older get vaccinated for covid-19. the known risks of covid-19 illness and its related, possibly severe complications, such as long-term health problems, hospitalization, and even death, far outweigh the potential risks of having a rare adverse reaction to vaccination, including the possible risk of myocarditis or pericarditis.
report an adverse event using the vaers online form or the downloadable pdf. new! given the high verification rate of reports of myocarditis to vaers after mrna-based covid-19 vaccination, underreporting is more likely. vaers data also first surfaced reports of myocarditis following the second dose of covid-19 mrna vaccine. after extensive review, scientists, .
main outcomes and measures: reports of myocarditis to vaers were adjudicated and summarized for all age groups. crude reporting rates were vaers received 1,991 reports of myocarditis, of which 1,626 met the cdc case definition for probable or confirmed myocarditis. among individuals what you need to know cases of myocarditis reported to the vaccine adverse event reporting system (vaers)external icon have occurred: both myocarditis and, .
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