vaers polio vaccine deaths

millions of vaccinations are given to children and adults in the united states each year. in the era of modern medicine, some of the first concerns about vaccines causing death date to isolated, but high profile past vaccine safety incidents. as a result of the association between the 1976 swine flu vaccine and guillain-barré syndrome, this condition is closely monitored every influenza season as part of the influenza vaccine safety monitoring in the united states. the death rate 1 or 2 months following vaccination was lower than that in the general us population, and the causes of death were similar [28]. the risk of anaphylaxis is less than two cases per million doses of vaccines administered to children and adolescents [29].

there is a small increased risk of intussusception associated with the rotavirus vaccines that are currently licensed and in use (rotateq® and rotarix®), but the risk is substantially lower than for rotashield® at approximately 1 case in 20,000 to 100,000 doses [41–43]. more than 60 cases worldwide have been reported to cdc and of those, 63% resulted in death [57]. naturally occurring smallpox disease has been eliminated worldwide, and in the united states, smallpox vaccine is currently only given to military personnel and selected individuals that might be at high risk of exposure, such as laboratory scientists that work with smallpox or similar viruses [63]. in fact, a review of the vaers data reveals that many of the death reports for mmr vaccine involved children with serious preexisting medical conditions or were likely unrelated to vaccination (e.g., accidents). disclosures: no authors have a conflict of interest, including specific financial interests and relationships and affiliations relevant to the subject matter or materials discussed in the manuscript.

our aim was to characterize main causes of death among reports submitted to the us vaccine adverse event reporting system (vaers), a spontaneous vaccine safety surveillance system. the main causes of death were consistent with the most common causes of death in the us population. for death reports, efforts are made to obtain autopsy reports and death certificates that contain information on the cause of death. pcv7 was licensed and recommended for use in 2000, and the first reports of death following pcv7 vaccination were reported that year (n = 20).

the rotavirus pentavalent vaccine (rv5) was licensed for use in 2006, and the first reports of death following rv5 occurred that year. this comprehensive review of death reports to vaers for the period 1 july 1997 through 31 december 2013 indicates that the most common causes of death in vaers were consistent with the leading causes of death in the us population (table 6) [13]. diseases of the circulatory system, the most common causes of death among vaers death reports in adults, are the leading causes of death in the us population. investigations into the causes of death in all these examples found that the vaccines were not implicated. continuous monitoring and assessment of death reports in vaers is warranted to ensure public confidence in the immunization program.

over 97% of reports were classified as non-serious. there were 2 deaths reported; no information in the reports or medical records suggested the deaths were only 78 such deaths were reported to vaers, suggesting not only that vaers does the institute of medicine (iom) reviewed deaths reported to vaers after vaccine-associated paralytic poliomyelitis (vapp) is a rare, diseases preventable by vaccine, diseases preventable by vaccine.

the 2149 deaths described in this study were reported to vaers during a period of time when approximately 2 billion doses of vaccine were distributed for use in c. shoulder injury related to vaccine administration death) of above events (interval – not applicable) b. vaccine-strain polio viral infection. illnesses, or deaths. date of death: (datedied): if the reporter checked that the vaccine pertussis vaccine + inactivated poliovirus vaccine +., .

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