federal government websites often end in .gov or .mil. the https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely. here, we present a thorough descriptive analysis of reports to a national passive vaccine safety surveillance system (vaers) of myopericarditis after vaccines licensed for use in the united states. methods: we identified u.s. reports of myopericarditis received by vaers during 1990-2018 that met a published case definition for myopericarditis or were physician-diagnosed.
we used empirical bayesian data mining to detect disproportionate reporting of myopericarditis after vaccination. overall, smallpox (59%) and anthrax (23%) vaccines were most commonly reported. the vaccines most commonly reported remained unchanged when excluding 138 reports describing other known causes of myopericarditis. conclusions: despite the introduction of new vaccines over the years, myopericarditis remains rarely reported after vaccines licensed for use in the united states. in this analysis, myopericarditis was most commonly reported after smallpox vaccine, and less commonly after other vaccines.
the data from the vaccine adverse event reporting system included 54 reports of guillain–barré syndrome after immunization that occurred in the usa in 2004 (4c). seventy percent of reports did not describe an adverse effect and the primary reason for report was vaccination during pregnancy. considering the observed data, hpv vaccine has a low risk of adverse events if given during pregnancy. the pattern of adverse events was similar to that reported for other vaccines given in the same age group except for reports of syncope and venous thromboembolic events (vtes).
there were 660 adverse events that met the inclusion criteria, 627 (95%) of which were reported to have occurred after primary immunization. the age and sex distributions of events reported after yellow fever immunization given alone were similar to those reported after immunization in combination with other vaccines. all but three of the severe adverse events occurred after primary vaccination and all the cases of neurological and viscerotropic disease occurred in primary vaccinees. sciencedirect ® is a registered trademark of elsevier b.v.
vaers accepts reports of adverse events that occur following vaccination. anyone, including healthcare providers, vaccine manufacturers, and the public can using the vaccine adverse event reporting system (vaers), researchers analyzed reports of adverse events (aes) following tdap in adults 65 years and older. from vaers is a national vaccine safety surveillance program that helps to detect unusual or unexpected reporting patterns of adverse events for vaccines. lite icon., .
results: vaers received 620,195 reports during 1990-2018: 708 (0.1%) met the case definition or were physician-diagnosed as myopericarditis. it’s a reporting system co-sponsored by the cdc and the fda. vaers data is analyzed from reports of adverse events following receipt of us-licensed vaccines all administrators of vaccines in the us are required to report adverse events via vaers. the methods and forms for reporting can be obtained by calling 800-, .
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