the rates of myocarditis cases were highest after the second vaccination dose in adolescent males aged 12 to 15 years (70.7 per million doses of the bnt162b2 vaccine), in adolescent males aged 16 to 17 years (105.9 per million doses of the bnt162b2 vaccine), and in young men aged 18 to 24 years (52.4 and 56.3 per million doses of the bnt162b2 vaccine and the mrna-1273 vaccine, respectively). the crude reporting rates for cases of myocarditis within 7 days after covid-19 vaccination exceeded the expected rates of myocarditis across multiple age and sex strata. in addition, reports from several countries raised concerns that mrna-based covid-19 vaccines may be associated with acute myocarditis.10-15 given this concern, the aims were to describe reports and confirmed cases of myocarditis initially reported to vaers after mrna-based covid-19 vaccination and to provide estimates of the risk of myocarditis after mrna-based covid-19 vaccination based on age, sex, and vaccine type. in cases of probable or confirmed myocarditis among those younger than 30 years of age, their clinical course was then summarized to the extent possible based on medical review and clinician interviews.
the lower estimate of the 95% ci for reporting rates of myocarditis in females exceeded the upper bound of the expected rates after the second vaccination dose with the bnt162b2 vaccine in those aged 12 to 29 years and after the second vaccination dose with the mrna-1273 vaccine in those aged 18 to 29 years. intravenous immunoglobulin and glucocorticoids were each used in 12% of the cases of myocarditis (78/676 and 81/676, respectively). however, it is expected that the rates in those older than 65 years of age would not be higher than the rates in those aged 50 to 64 years.4 based on passive surveillance reporting in the us, the risk of myocarditis after receiving mrna-based covid-19 vaccines was increased across multiple age and sex strata and was highest after the second vaccination dose in adolescent males and young men. the authors affiliated with the cdc along with the other coauthors conducted the investigations; performed collection, management, analysis, and interpretation of the data; were involved in the preparation, review, and approval of the manuscript; and made the decision to submit the manuscript for publication.
the authors also concluded that the risk of hospitalization for cardiac adverse events following vaccination is higher than the risk of being hospitalized with covid for healthy boys in both age groups. høeg said the group used the same definition of myocarditis that the cdc did for its previous estimates using vaers data, and that cardiologist mandrola was key in vetting reports. she said they also wanted to stratify risk by age groups 12-15 and 16-17, which cdc hadn’t done: “as a mom of 10- and 13-year-old boys, this was important information for me to see and i know many other parents feel the same way.” høeg has a phd in epidemiology and public health from the university of copenhagen, but her medical specialty is physical medicine & rehabilitation.
josh stevenson lists truth in data, as his primary affiliation on the paper, and is also listed under the “team” page at rational ground, where he is described as a “data visualization expert who focuses on creating easy to understand charts and dashboards with data,” with a background in computer systems engineering. i just know that the result is definitely not good, and the involvement of josh stevenson in particular makes this whole study very suspect indeed.” but, from the evidence we have thus far: “it’s not yet clear how large the risk of myocarditis is in this age group.” medpage today is among the federally registered trademarks of medpage today, llc and may not be used by third parties without explicit permission.
report an adverse event using the vaers online form or the downloadable pdf. new! important: if you are experiencing a medical emergency, seek immediate vaers data also first surfaced reports of myocarditis following the second dose of covid-19 mrna vaccine. after extensive review, scientists given the high verification rate of reports of myocarditis to vaers after mrna-based covid-19 vaccination, underreporting is more likely., vaers id 1074247, vaers id 1074247, vaers lymphoma, vaers i.d. 1242573, the vaccine adverse events reporting system is quizlet.
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