following review of data for the covid-19 vaccine moderna vaccine, the mhra and commission on human medicine (chm) experts also concluded that this vaccine can be used as a safe and effective booster dose. the majority of adverse reactions were mild to moderate in severity and usually resolved within a few days after vaccination. vaccines are the best way to protect people from covid-19 and have already saved tens of thousands of lives. in relation to covid-19 vaccines, the mhra has authorised their supply following a rigorous review of their safety, quality and efficacy. some children aged 5 to 11 have been eligible for a first and second dose of the covid-19 vaccine if either they have a condition that means they are at high risk of serious illness from covid-19 or they live with someone who has a weakened immune system. the first report was received on 9 december 2020. up to and including 25 may 2022, the mhra received and analysed a total of 245,400 uk reports of suspected adrs to the covid-19 vaccine astrazeneca. one of the mhra’s main roles is to continually monitor the safety of medicines and vaccines during widespread use, and we have in place a proactive strategy to do this for covid-19 vaccines. as we receive more reports of these types of reactions with more exposure to the covid-19 vaccines, we have built a picture of how individuals are experiencing them and the different ways that side effects may present in people. the current advice of the joint committee on vaccination and immunisation (jcvi) is that the covid-19 vaccines should be offered to those who are pregnant as a clinical risk group in the covid-19 vaccination programme. the product information for covid-19 pfizer/biontech vaccine and covid-19 vaccine moderna has been updated to reflect the new safety data and that the vaccines can be used during pregnancy. for the covid-19 pfizer/biontech vaccine, which is currently the preferred covid-19 vaccine for the under 18s age group in the uk vaccination programme, the experience reported in under 18s is similar to that identified in the general population and a review of these reports does not raise any additional safety topics specific to this age group. for the covid-19 vaccine astrazeneca there has been very limited number of booster doses in the uk and a very small number of reports. the mhra is closely monitoring reports of anaphylaxis with the covid-19 vaccine moderna and has received 93 reports of anaphylaxis in association with the vaccine. tm is known to be associated with a number of viruses, such as the herpes and influenza virus.
the estimated number of first doses of covid-19 vaccine astrazeneca administered in the uk by 25 may was 24.9 million and the estimated number of second doses was 24.1 million. however, the data are reassuring, particularly regarding younger recipients where there is a significantly lower incidence after the second dose compared to the first, and there is overall no indication of an increased risk of these events after the second dose in any age group. following the most recent review, the available data suggested a possible link between covid-19 vaccine astrazeneca and itp, and the product information for this vaccine has been updated to include information on the occurrence of itp. there has been a consistent pattern of higher reporting of these suspected events with the covid-19 pfizer/biontech and covid-19 vaccine moderna, and of these occurring more frequently in males. pfizer/biontech is currently the preferred covid-19 vaccine for the under 18s age group in the uk vaccination programme, and for this vaccine there is no indication in the current data that there is an increased reporting rate of suspected myocarditis and pericarditis in this age group overall compared to young adults. due to this limited usage and very small numbers of reports of suspected myocarditis and pericarditis after booster doses, it is not possible to calculate a reliable reporting rate for the covid-19 vaccine astrazeneca when used as a booster; no association has been established between myocarditis or pericarditis and the covid-19 vaccine astrazeneca. the majority of the reports received have been with the covid-19 vaccine moderna and the product information for this vaccine has been updated to highlight the possibility of delayed injection site reactions. the product information for the covid-19 pfizer/biontech vaccine has been updated to include facial swelling in those with a history of injection of facial dermatological fillers as a side effect of the vaccine. the mhra has received 778 uk reports of suspected adrs to the covid-19 pfizer/biontech vaccine in which the patient died shortly after vaccination, 1,277 reports for the covid-19 vaccine astrazeneca, 59 for the covid-19 vaccine moderna and 47 where the brand of vaccine was unspecified. a list of the recognised adverse effects of covid-19 vaccines is provided in the information for healthcare professionals and the recipient information here. for a medicine or vaccine to be considered safe, the expected benefits will be greater than the risk of having harmful reactions. epidemiological studies include large numbers of people and are designed to compare the risk of a particular event in an exposed population, in this case those who have received a vaccine, to those who have not. the mhra’s scheme for healthcare professionals and members of the public to report suspected adverse reactions for a medicine or vaccine, as well as medical devices and other products. ↩ the green book has the latest information on vaccines and vaccination procedures, for vaccine preventable infectious diseases in the uk.
important: if you are experiencing a medical emergency, seek immediate assistance from a healthcare provider or call 9-1-1. cdc and fda do not provide vaers data csv and compressed (zip) files are available for download in the table below. for information about vaers data, please view the pdf icon information provided to vaers which identifies a person who received the vaccine or vaccines will not be made available to the public. de-identified vaers data, .
to search articles on this page by keyword, first click the “open all” tab to list all publications. then use the “find on this page” function available in while very important in monitoring vaccine safety, vaers reports alone cannot be used to determine if a vaccine caused or contributed to an adverse event or at the time of this report, over 178,448 people across the uk have died within 28 days of a positive test for coronavirus (covid-19). vaccination is the single, .
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